IMS protein | MW (kDa) | Function | References |
---|---|---|---|
Cytochrome c | 12 | Apaf-1 binding and apoptosome initiation | |
SMAC/DIABLO | 23 | Neutralization of apoptosis inhibitor factors | |
OMI/HTRA2 | 37 | Neutralization of apoptosis inhibitor factors | |
AIF | 62 | DNA fragmentation | |
ENDOG | 28 | DNA fragmentation | [55] |
AK2, Adenylate Kinase 2 | 26 | Initiation of AK2-FADD-caspase-10 complex | [60] |