Table 3 List of variants of uncertain significance
From: Diagnostic yield of array CGH in patients with autism spectrum disorder in Hong Kong
Patient number | Gender/group | Array CGH result [hg18] | Chromosome region | Aberration type | Size (Mb) | IQ | Additional clinical features |
|---|---|---|---|---|---|---|---|
9 | Male/adult | arr 3q13.3 (111,747,166–112,297,084) × 3 | 3q13.3 | Duplication | 0.55 | 96 | Nil |
10 | Male/adult | arr 1q44 (244,474,644–245,087,421) × 3 | 1q44 | Duplication | 0.61 | 85 | Nil |
11 | Female/adult | arr 11q24.1 (122,330,312–122,406,276) × 3 | 11q24.1 | Duplication | 0.08 | 103 | Nil |
12 | Female/paediatric | arr 10p12.33p12.32 (19,502,326–20,471,711) × 3 | 10p12.33–p12.32 | Duplication | 0.97 | N/A | Scoliosis |
13 | Male/paediatric | arr 17q21.33 (45,861,307–45,986,282) × 3 | 17q21.33 | Duplication | 0.12 | N/A | Developmental delay |
14 | Male/paediatric | arr 6q14.1 (82,900,869–83,543,710) × 3 | 6q14.1 | Duplication | 0.64 | N/A | Developmental delay/regression, asthma, severe eczema |
15 | Male/paediatric | arr 5q33.1 (148,226,533–148,809,596) × 1 | 5q33.1 | Deletion | 0.58 | N/A | Nil |