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Fig. 6 | Clinical and Translational Medicine

Fig. 6

From: Depurinating estrogen-DNA adducts, generators of cancer initiation: their minimization leads to cancer prevention

Fig. 6

Depurinating adducts formed by mixtures of a E2-3,4-Q and E2-2,3-Q at different ratios after 10 h of reaction with DNA. The level of stable adducts formed in the mixtures ranged from 0.1 to 1 % of total adducts; and b 4-OHE2 and 2-OHE2 in the presence of tyrosinase at different ratios after 10 h of reaction with DNA. The level of stable adducts formed in the mixtures ranged from 0.1 to 0.7 % of total adducts [26]

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