Fig. 1
From: Targeting polo-like kinase 1, a regulator of p53, in the treatment of adrenocortical carcinoma
High PLK1 mRNA expression is associated with worse prognosis in ACC tumors. a In data from Affymetrix U133 plus 2 arrays, tumors that exhibit a log2 fold-change of 2 or greater relative to normal have a worse overall survival compared to tumors that express less PLK1 mRNA. b The relationship between PLK1 mRNA expression and shorter survival times was validated by RNA sequencing data from TCGA. c In the TCGA data set, the only clinical parameter associated with PLK1 expression is residual tumor status