Fig. 9From: A novel, clinically relevant use of a piglet model to study the effects of anesthetics on the developing brainBasal ganglia infarct in an animal administered isoflurane. This composite of four panels shows a control animal (panels a and b) and an ischemic insult in an animal who was administered isoflurane (panels c and d). Panel c is characterized by the “shaggy” appearance of the brain tissue damage and hypereosiniphilic neurons (black arrows; panel d). Note the pericellular edema (white halos). This piglet suffered no periods of hypoxia or hypotension and electrolytes were normal at all times. It is critical to identify if this is an anesthetic effectBack to article page