Plasma preparation to measure FDA-approved protein markers by selected reaction monitoring

Clinical and Translational Medicine

Table 1 Examples of protein detection in 19 plasma samples using the PlasmaDeepDive™ kit and SpectroDive™ software with a q value <0.01

Protein	Reproducibility of detection in all series, %	Series #1				Series #2				Series #3
		Total^a	Number of tech. runs			Total^a	Number of tech. runs			Total^a	Number of tech. runs
		Total^a	1	2	3	Total^a	1	2	3	Total^a	1	2	3
Apolipoprotein A1	100	57			19	57			19	57			19
Serum albumin	99	57			19	57			19	55		2	17
Insulin-like growth factor-binding protein 3	70	10	2	1	2	56		1	18	53		4	15
Cystatin-C	33	7	2	1	1	23	5	3	4	27	5	5	4
von Willebrand factor	5	0	0			1	1			8	4	2

^aTotal: number of technical runs in which the peptide was detected, multiplied by the number of samples