Fig. 1

Gene ontology (GO) analysis for three cancer groups, AIS, MIA and LPIA, in which utilized were 544, 607, and 789 proteins, respectively, identified with SpC > 2. a Biological process: 1, cellular component organization or biogenesis (GO:0071840); 2, cellular process (GO:0009987); 3, localization (GO:0051179); 4, apoptotic process (GO:0006915); 5, reproduction (GO:0000003); 6, biological regulation (GO:0065007); 7, response to stimulus (GO:0050896); 8, developmental process (GO:0032502); 9, multicellular organismal process (GO:0032501); 10, biological adhesion (GO:0022610); 11, metabolic process (GO:0008152); 12, immune system process (GO:0002376). b Protein class: 1 extracellular matrix protein (PC00102); 2, protease (PC00190); 3, cytoskeletal protein (PC00085); 4, transporter (PC00227); 5, transmembrane receptor regulatory/adaptor protein (PC00226); 6, transferase (PC00220); 7, oxidoreductase (PC00176); 8, lyase (PC00144); 9, cell adhesion molecule (PC00069); 10, ligase (PC00142); 11, nucleic acid binding (PC00171); 12, signaling molecule (PC00207); 13, enzyme modulator (PC00095); 14, calcium-binding protein (PC00060); 15, defense/immunity protein (PC00090); 16, hydrolase (PC00121); 17, transfer/carrier protein (PC00219); 18, membrane traffic protein (PC00150); 19, phosphatase (PC00181); 20, transcription factor (PC00218); 21, chaperone (PC00072); 22, cell junction protein (PC00070); 23, surfactant (PC00212); 24, structural protein (PC00211); 25, kinase (PC00137); 26, storage protein (PC00210); 27, receptor (PC00197); 28, isomerase (PC00135)