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Table 5 Performance of individual marker in primary and metastatic lung squamous cell carcinomas

From: Utility of five commonly used immunohistochemical markers TTF-1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases

Type

Primary SqCC (n = 30) vs

Metastatic SqCC (n = 13) vs

Primary ADC (n = 72)

Metastatic ADC (n = 131)

Sensitivity

Specificity

PPV

NPV

Sensitivity

Specificity

PPV

NPV

P63

91.7%

78.3%

81.5%

90.0%

100.0%

68.4%

64.7%

100.0%

CK5/6

100.0%

77.8%

90.0%

100.0%

100.0%

84.6%

75.0%

100.0%

  1. ADC: adenocarcinoma. SqCC: squamous cell carcinoma. PPV: positive predictive value. NPV: negative predictive value.