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Table 4 Immunostaining patterns in primary and metastatic NSCLC

From: Utility of five commonly used immunohistochemical markers TTF-1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases

NSCLC

P63

CK5/6

Napsin A

TTF-1

CK7

Positive/total

Positive/total

Positive/total

Positive/total

Positive/total

(%)

(%)

(%)

(%)

(%)

Primary lung carcinomas (n = 102)

ADC (n = 72)

5/23

2/9

23/25

60/71

45/48

 

(21.7%)

(22.2%)

(92.0%)

(84.5%)

(93.8%)

SqCC (n = 30)

22/24

18/18

0/8

1/28

7/14

 

(91.7%)

(100.0%)

(0.0%)

(3.6%)

(50.0%)

Metastatic tumor of the lung (n = 143)

ADC (n = 131)

6/19

2/13

40/59

113/130

101/101

 

(31.6%)

(15.4%)

(67.8%)

(86.9%)

(100.0%)

SqCC (n = 13)

11/11

6/6

0/3

1/8

3/4

 

(100.0%)

(100.0%)

(0.0%)

(12.5%)

(75.0%)

  1. NSCLC: non-small cell lung carcinoma. ADC: adenocarcinoma. SqCC: squamous cell carcinoma.