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Table 3 Clinicopathological correlation with KIAA1549-BRAF fusion status in patients with LGG

From: Incidence of kiaa1549-braf fusion gene in Egyptian pediatric low grade glioma

 

Total

Positive

Negative

p-value

Tumor examined

60

34(56.6%)

26(43.3%)

 

Tumor location

    

Cerebellar

37(61%)

26(70.2%)

11(29.2%)

0.008*

Lobar

15(25%)

5(33.3%)

10(66.6%)

0.068

Spinal cord

3(5%)

2(66.6%)

1(33.3%)

1

Optic pathway

2(3.3%)

0

2(100%)

0.18

Pathology

    

PAs

31(51.6%)

23(74.2%)

8(25.8%)

0.008*

PMAs

15(25%)

9(60%)

6(40%)

0.769

DAs

3(5%)

0

3(100%)

 

PXA

2(3.3%)

0

2(100%)

 

LGGN

9(15%)

2(22.2%)

7(77.7%)

0.032*

Gender

    

Females

26(43.3%)

16(61.5%)

10(38.4%)

0.79

Males

34(56.5%)

19(55.8%)

15(44.1%)

 
  1. PAs, pilocytic astrocyoma; PMAs, pilomyxoid astrocyoma; PXA, pleomophicxantho astrocytoma; LGGN (low grade glioneuronal); DAs, (diffuse astrocytom)a. *Fisher’s exact test (P > 0.05).