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Table 1 The Sharklet micropattern reduces bacterial colonization after blood protein treatment LD: ANOVA determination of Average LogCFU/50 mm2; SEM: Standard error of the Mean; Conditions that share the same statistical group are not significantly different with p > 0.05

From: An engineered micropattern to reduce bacterial colonization, platelet adhesion and fibrin sheath formation for improved biocompatibility of central venous catheters

Organism

Agitation

Incubation period (hr)

Pre-condition media

Unpatterned LD (SEM)

−3SK2x2 LD (SEM)

Percent Reduction

p value

cpi

S. aureus ATCC 6538

Static

1

Saline

4.05 (0.17)

3.17 (0.20)

94%

0.001

A

A

Whole Blood

3.82 (0.13)

3.37 (0.16)

83%

0.003

18

Saline

4.91 (0.25)

3.91 (0.21)

89%

0.019

A

Whole Blood

3.71 (0.29)

3.23 (0.31)

70%

0.048

A

Dynamic

1

Saline

5.23 (0.22)

4.79 (0.16)

64%

0.128

A

Whole Blood

4.5 (0.21)

3.9 (0.37)

74%

0.128

A

18

Saline

5.66 (0.1)

4.82 (0.19)

85%

0.008

A

Whole Blood

4.49 (0.17)

4.06 (0.23)

63%

0.032

A

S. epidermidis ATCC 35984

Static

1

Saline

5.04 (0.09)

4.23 (0.15)

84%

0.065

A

25% Serum

3.68 (0.08)

3.24 (0.12)

64%

0.005

A

18

Saline

5.06 (0.1)

3.92 (0.1)

91%

0.001

A

25% Serum

3.84 (0.09)

3.47 (0.12)

71%

0.003

A