Figure 4From: An engineered micropattern to reduce bacterial colonization, platelet adhesion and fibrin sheath formation for improved biocompatibility of central venous catheters The Sharklet micropattern reduces fibrin sheath formation resulting from platelet activation. Representative images of immunostained fibrinogen on (a) unpatterned, (b) +3SK2x2 and (c) -3SK2x2 TPU surfaces. Quantification of fluorescent images revealed that both Sharklet micropatterns significantly reduce fibrinogen area coverage compared to unpatterned controls. Scale bar, 50 μm.Back to article page