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Clinical and Translational Medicine
Figure 5 | Clinical and Translational Medicine

Figure 5

From: Hallmarks of epithelial to mesenchymal transition are detectable in Crohn’s disease associated intestinal fibrosis

Figure 5

FAP expression is strongly detectable in myofibroblasts adjacent to fibrotic areas. Representative images show (A) van-Gieson staining and (B) corresponding FAP staining in fibrotic tissue samples derived from CD patients. (B-D) FAP staining is strongly detectable in myofibroblasts adjacent to the fibrotic areas (black arrows), while FAP staining in myofibroblasts within fibrotic areas is limited (white arrows). Magnification: 10-fold. All analysed patient samples showed comparable staining characteristics when compared to samples from non-affected controls.

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