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Clinical and Translational Medicine
Figure 1 | Clinical and Translational Medicine

Figure 1

From: MELK—a conserved kinase: functions, signaling, cancer, and controversy

Figure 1

The domains essential for the kinase activity, namely the kinase, UBA and KA1 domain are highlighted. The numbers indicate the % of identical/conserved residues in the different domains (kinase + UBA domain residues 11-326, variable domain 327-600, KA1 residues 601-651 in human MELK) for the different species compared to human Melk (H. sapiens) as revealed by a Blast search.

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