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Table 2 Vaccination protocols in allergic subjects

From: Vaccination in children with allergy to non active vaccine components

Allergen Vaccine Vaccination protocol Setting
Egg Yellow fever* Rabies* ° Influenza MMR Tick-borne en- cephalitis MMR and Influenza:  
1) If egg-allergy normally administer with a 60 minutes observation 1) Office
2) If egg-anaphylaxis normally administer with a 60 minutes observation 2) Hospital
Yellow fever:  
1) If skin tests are negative: normally administer with a 60 minutes observation Hospital
2) If skin tests are positive: desensitization/graded doses
Cow’s milk OPV, DTP, DT, DTaP, PCV-13 If previous anaphylaxis normally administer with a 60 minutes observation Office
Yeasts Hepatitis B, Quadrivalent HPV, meningococcal , PCV-13, typhoid (oral) 1) If skin tests with vaccine are negative: normally ad- minister with a 60 minutes observation Hospital
2) If skin tests with vaccine are positive: desensitiza- tion/graded doses
Neomycin MMR, IPV, rabies, influenza, varicella, Zoster HepA 1) If local skin reaction: normally administer Office/Hospital
2) If anaphylactic reaction: no vaccine
Gelatin MMR*, Varicella*, Zooster*, Yellow fever* Rabies °, DTP Influenza 1) If skin tests are negative: normally administered with a 60 minutes observation Hospital
2) If skin tests are positive: gelatin-free vaccine or de- sensitization/graded doses
Latex When vaccine has no removable contaminated part (prefilled syringe), vaccine should be normally administered with a 60 minutes observation Hospital
  1. *High amount. °To be used when polygeline free and egg free vaccine is unavailable.