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Clinical and Translational Medicine

Table 3 Ct-OATP1B3 and Lt-OATP1B3 mRNA levels in colon tissues and pooled human hepatocytes

From: Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers

mRNA name

Tissue (n)a

Median value (25-75thpercentile)(×103copies/ng total RNA)

Ct-OATP1B3

Cancer (34)

19.5 (5.3-50.2)

 

Normal (1)

N/Ab

 

Pooled hepatocytes

N/Ac

Lt-OATP1B3

Cancer (21)

1.6 (1.2-2.4)

 

Normal (20)

1.4 (1.2-1.7)

 

Pooled hepatocytes

56.9 ± 2.5d

  1. aThe number of Ct-OATP1B3 or Lt-OATP1B3 mRNA positive patients is shown in parentheses.
  2. bThe Ct-OATP1B3 mRNA copy number in the normal tissue is 4.3 × 103 copies/ng total RNA.
  3. cThe Ct-OATP1B3 mRNA expression level in pooled hepatocytes is under the quantification limit.
  4. dThe Lt-OATP1B3 mRNA expression level in pooled hepatocytes is expressed as the mean value ± SD.
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