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Clinical and Translational Medicine
Figure 4 | Clinical and Translational Medicine

Figure 4

From: Gene expression profiling of immunomagnetically separated cells directly from stabilized whole blood for multicenter clinical trials

Figure 4

Visualization of the enrichment of CD45+ cells. (A) Expression profiles of CD45 and Hemoglobin delta from five donors. Expression levels indicate a 99% positive selection rate of CD45+ cells compared to blood, and a 97% enrichment compared to PBMC fractions. (B) The expression levels of platelet-expressed transcripts are markedly reduced in CD45+ samples, indicating an enrichment of CD45+ cells. Expression level reduction of genes expressed in blood but not in purified CD45+ cells indicate a 97% enrichment of CD45+. Mean values per group and the standard error of mean are shown.

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