TY - JOUR AU - Fischgrabe, J. AU - Wulfing, P. PY - 2009 DA - 2009// TI - Targeted therapies in breast cancer: established drugs and recent developments JO - Curr Clin Pharmacol VL - 3 UR - https://doi.org/10.2174/157488408784293732 DO - 10.2174/157488408784293732 ID - Fischgrabe2009 ER - TY - JOUR AU - Prat, M. AU - Narsimhan, R. P. AU - Crepaldi, T. AU - Nicotra, M. R. AU - Natali, P. G. AU - Comoglio, P. M. PY - 1991 DA - 1991// TI - The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors JO - Int JCancer VL - 49 UR - https://doi.org/10.1002/ijc.2910490302 DO - 10.1002/ijc.2910490302 ID - Prat1991 ER - TY - JOUR AU - Naran, S. AU - Zhang, X. AU - Hughes, S. J. PY - 2009 DA - 2009// TI - Inhibiton of HGF/Met as therapy for malignancy JO - Expert Opin Ther Targets VL - 13 UR - https://doi.org/10.1517/14728220902853917 DO - 10.1517/14728220902853917 ID - Naran2009 ER - TY - JOUR AU - Gentile, A. AU - Trusolino, L. AU - Comoglio, P. M. PY - 2008 DA - 2008// TI - The Met tyrosine kinase receptor in development and cancer JO - Cancer Metastasis Rev VL - 27 UR - https://doi.org/10.1007/s10555-007-9107-6 DO - 10.1007/s10555-007-9107-6 ID - Gentile2008 ER - TY - JOUR AU - Gastaldi, S. AU - Comoglio, P. M. AU - Trusolino, L. PY - 2010 DA - 2010// TI - The Met oncogene and basal-like breast cancer: another culprit to watch out for? JO - Breast Cancer Res VL - 12 UR - https://doi.org/10.1186/bcr2617 DO - 10.1186/bcr2617 ID - Gastaldi2010 ER - TY - JOUR AU - Geho, D. H. AU - Bandle, R. W. AU - Clair, T. AU - Liotta, L. A. PY - 2005 DA - 2005// TI - Physiological mechanisms of tumor-cell invasion and migration JO - Physiology (Bethesda) VL - 20 UR - https://doi.org/10.1152/physiol.00009.2005 DO - 10.1152/physiol.00009.2005 ID - Geho2005 ER - TY - JOUR AU - Porter, A. C. AU - Vaillancourt, R. R. PY - 1998 DA - 1998// TI - Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis JO - Oncogene VL - 17 UR - https://doi.org/10.1038/sj.onc.1202171 DO - 10.1038/sj.onc.1202171 ID - Porter1998 ER - TY - JOUR AU - Elliott, B. E. AU - Hung, W. L. AU - Boag, A. H. AU - Tuck, A. B. PY - 2002 DA - 2002// TI - The role of hepatocyte growth factor (scatter factor) in epithelial-mesenchymal transition and breast cancer JO - Can J Physiol Pharmacol VL - 80 UR - https://doi.org/10.1139/y02-010 DO - 10.1139/y02-010 ID - Elliott2002 ER - TY - JOUR AU - Sattler, M. AU - Salgia, R. PY - 2007 DA - 2007// TI - c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy JO - Curr Oncol Rep VL - 9 UR - https://doi.org/10.1007/s11912-007-0005-4 DO - 10.1007/s11912-007-0005-4 ID - Sattler2007 ER - TY - JOUR AU - Eder, J. P. AU - Vande Woude, G. F. AU - Boerner, S. A. AU - LoRusso, P. M. PY - 2009 DA - 2009// TI - Novel therapeutic inhibitors of the c-Met signaling pathway in cancer JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-08-1306 DO - 10.1158/1078-0432.CCR-08-1306 ID - Eder2009 ER - TY - JOUR AU - Cooke, V. G. AU - LeBleu, V. S. AU - Keskin, D. AU - Khan, Z. AU - O'Connell, J. T. AU - Teng, Y. AU - Duncan, M. B. AU - Xie, L. AU - Maeda, G. AU - Vong, S. AU - Sugimoto, H. AU - Rocha, R. M. AU - Damascena, A. AU - Brentani, R. R. AU - Kalluri, R. PY - 2012 DA - 2012// TI - Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway JO - Cancer Cell VL - 21 UR - https://doi.org/10.1016/j.ccr.2011.11.024 DO - 10.1016/j.ccr.2011.11.024 ID - Cooke2012 ER - TY - JOUR AU - Tomaskovic-Crook, E. AU - Thompson, E. W. AU - Thiery, J. P. PY - 2009 DA - 2009// TI - Epithelial to mesenchymal transition and breast cancer JO - Breast Cancer Res VL - 11 UR - https://doi.org/10.1186/bcr2416 DO - 10.1186/bcr2416 ID - Tomaskovic-Crook2009 ER - TY - JOUR AU - Ma, P. C. AU - Maulik, G. AU - Christensen, J. AU - Salgia, R. PY - 2003 DA - 2003// TI - c-Met: structure, functions and potential for therapeutic inhibition JO - Cancer Metastasis Rev VL - 22 UR - https://doi.org/10.1023/A:1023768811842 DO - 10.1023/A:1023768811842 ID - Ma2003 ER - TY - JOUR AU - Nagai, T. AU - Arao, T. AU - Furuta, K. AU - Sakai, K. AU - Kudo, K. AU - Kaneda, H. AU - Tamura, D. AU - Aomatsu, K. AU - Kimura, H. AU - Fujita, Y. AU - Matsumoto, K. AU - Saijo, N. AU - Kudo, M. AU - Nishio, K. PY - 2011 DA - 2011// TI - Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma JO - Mol Cancer Ther VL - 10 UR - https://doi.org/10.1158/1535-7163.MCT-10-0544 DO - 10.1158/1535-7163.MCT-10-0544 ID - Nagai2011 ER - TY - JOUR AU - Reshetnikova, G. AU - Troyanovsky, S. AU - Rimm, D. L. PY - 2007 DA - 2007// TI - Definition of a direct extracellular interaction between met and E-cadherin JO - Cell Biol Int VL - 31 UR - https://doi.org/10.1016/j.cellbi.2007.01.022 DO - 10.1016/j.cellbi.2007.01.022 ID - Reshetnikova2007 ER - TY - JOUR AU - Micalizzi, D. S. AU - Farabaugh, S. M. AU - Ford, H. L. PY - 2010 DA - 2010// TI - Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression JO - J Mammary Gland Biol Neoplasia VL - 15 UR - https://doi.org/10.1007/s10911-010-9178-9 DO - 10.1007/s10911-010-9178-9 ID - Micalizzi2010 ER - TY - JOUR AU - Takebe, N. AU - Warren, R. Q. AU - Ivy, S. P. PY - 2011 DA - 2011// TI - Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition JO - Breast Cancer Res VL - 13 UR - https://doi.org/10.1186/bcr2876 DO - 10.1186/bcr2876 ID - Takebe2011 ER - TY - JOUR AU - Hu, J. AU - Shao, S. AU - Song, Y. AU - Zhao, J. AU - Dong, Y. AU - Gong, L. AU - Yang, P. PY - 2010 DA - 2010// TI - Hepatocyte growth factor induces invasion and migration of ovarian cancer cells by decreasing the expression of E-cadherin, beta-catenin, and caveolin-1 JO - Anat Rec (Hoboken) VL - 293 UR - https://doi.org/10.1002/ar.21147 DO - 10.1002/ar.21147 ID - Hu2010 ER - TY - JOUR AU - Singh, A. AU - Settleman, J. PY - 2010 DA - 2010// TI - EMT, cancer stem cells and drug reistance: and emerging axis of evil in the war on cancer JO - Oncogene VL - 29 UR - https://doi.org/10.1038/onc.2010.215 DO - 10.1038/onc.2010.215 ID - Singh2010 ER - TY - JOUR AU - Ke, Q. AU - Costa, M. PY - 2006 DA - 2006// TI - Hypoxia-inducible factor-1 (HIF-1) JO - Mol Pharmacol VL - 70 UR - https://doi.org/10.1124/mol.106.027029 DO - 10.1124/mol.106.027029 ID - Ke2006 ER - TY - JOUR AU - Wang, G. L. AU - Jiang, B. H. AU - Rue, E. A. AU - Semenza, G. L. PY - 1995 DA - 1995// TI - Hypoxia-inducible factor 1 is a basic-helix-loop-helix-pas heterodimer regulated by cellular O2 tension JO - Proc Natl Acad Sci USA VL - 92 UR - https://doi.org/10.1073/pnas.92.12.5510 DO - 10.1073/pnas.92.12.5510 ID - Wang1995 ER - TY - JOUR AU - Pennacchietti, S. AU - Michieli, P. AU - Galluzzo, M. AU - Mazzone, M. AU - Giordano, S. AU - Comoglio, P. M. PY - 2003 DA - 2003// TI - Hypoxia promotes invasive growth by transcriptional activation of the Met protooncogene JO - Cancer Cell VL - 3 UR - https://doi.org/10.1016/S1535-6108(03)00085-0 DO - 10.1016/S1535-6108(03)00085-0 ID - Pennacchietti2003 ER - TY - JOUR AU - Bussolino, F. AU - Di Renzo, M. F. AU - Ziche, M. AU - Bocchietto, E. AU - Olivero, M. AU - Naldini, L. AU - Gaudino, G. AU - Tamagnone, L. AU - Coffer, A. AU - Comoglio, P. M. PY - 1992 DA - 1992// TI - Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth JO - J Cell Biol VL - 119 UR - https://doi.org/10.1083/jcb.119.3.629 DO - 10.1083/jcb.119.3.629 ID - Bussolino1992 ER - TY - JOUR AU - Ayoub, N. M. AU - Bachawal, S. V. AU - Sylvester, P. W. PY - 2011 DA - 2011// TI - γ-Tocotrienol inhibits Met expression and activation in highly malignant mammary tumor cells JO - Cell Proliferation VL - 44 UR - https://doi.org/10.1111/j.1365-2184.2011.00785.x DO - 10.1111/j.1365-2184.2011.00785.x ID - Ayoub2011 ER - TY - JOUR AU - Ayoub, N. M. AU - Akl, M. R. AU - Sylvester, P. W. PY - 2013 DA - 2013// TI - Combined γ-tocotrienol and Met inhibitor treatment suppresses cancer cell proliferation, epithelial-to-mesenchymal transition, and migration JO - Cell Proliferation VL - 46 ID - Ayoub2013 ER - TY - JOUR AU - Toschi, L. AU - Janne, P. A. PY - 2008 DA - 2008// TI - Single-agent and combination therapeutic strategies to inhibit hepatocyte growth factor/Met signaling in cancer JO - Clin Cancer Res VL - 14 UR - https://doi.org/10.1158/1078-0432.CCR-08-0071 DO - 10.1158/1078-0432.CCR-08-0071 ID - Toschi2008 ER - TY - JOUR AU - Knudsen, B. S. AU - Vande Woude, G. PY - 2008 DA - 2008// TI - Showering c-Met-dependent cancers with drugs JO - Curr Opin Genet Dev VL - 19 UR - https://doi.org/10.1016/j.gde.2008.02.001 DO - 10.1016/j.gde.2008.02.001 ID - Knudsen2008 ER - TY - JOUR AU - Stellrecht, C. M. AU - Gandhi, V. PY - 2009 DA - 2009// TI - Met receptor tyrosine kinase as a therapeutic anticancer target JO - Cancer Lett VL - 280 UR - https://doi.org/10.1016/j.canlet.2008.10.045 DO - 10.1016/j.canlet.2008.10.045 ID - Stellrecht2009 ER - TY - JOUR AU - Liu, X. AU - Yao, W. AU - Newton, R. C. AU - Scherle, P. A. PY - 2008 DA - 2008// TI - Targeting the c-Met signaling pathway for cancer therapy JO - Expert Opin Investig Drugs VL - 17 UR - https://doi.org/10.1517/13543784.17.7.997 DO - 10.1517/13543784.17.7.997 ID - Liu2008 ER - TY - JOUR AU - Graveel, C. R. AU - DeGroot, J. D. AU - Su, Y. AU - Koeman, J. AU - Dykema, K. AU - Leung, S. AU - Snider, J. AU - Davies, S. R. AU - Swiatek, P. J. AU - Cottingham, S. AU - Watson, M. A. AU - Ellis, M. J. AU - Sigler, R. E. AU - Furge, K. A. AU - Vande Woude, G. F. PY - 2009 DA - 2009// TI - Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer JO - Proc Natl Acad Sci USA VL - 106 UR - https://doi.org/10.1073/pnas.0810403106 DO - 10.1073/pnas.0810403106 ID - Graveel2009 ER - TY - JOUR AU - Lee, J. H. AU - Han, S. U. AU - Cho, H. AU - Jennings, B. AU - Gerrard, B. AU - Dean, M. AU - Schmidt, L. AU - Zbar, B. AU - Vande Woude, G. F. PY - 2000 DA - 2000// TI - A novel germ line juxtamembrane Met mutation in human gastric cancer JO - Oncogene VL - 19 UR - https://doi.org/10.1038/sj.onc.1203874 DO - 10.1038/sj.onc.1203874 ID - Lee2000 ER - TY - JOUR AU - Bellon, S. F. AU - Kaplan-Lefko, P. AU - Yang, Y. AU - Zhang, Y. AU - Moriguchi, J. AU - Rex, K. AU - Johnson, C. W. AU - Rose, P. E. AU - Long, A. M. AU - O'Connor, A. B. AU - Gu, Y. AU - Coxon, A. AU - Kin, T. S. AU - Tasker, A. AU - Burgess, T. L. AU - Dussault, I. PY - 2008 DA - 2008// TI - c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations JO - J Biol Chem VL - 283 UR - https://doi.org/10.1074/jbc.M705774200 DO - 10.1074/jbc.M705774200 ID - Bellon2008 ER - TY - JOUR AU - Agarwal, S. AU - Zerillo, C. AU - Kolmakova, J. AU - Christensen, J. G. AU - Harris, L. N. AU - Rimm, D. L. AU - Digiovanna, M. P. AU - Stern, D. F. PY - 2009 DA - 2009// TI - Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells JO - Br J Cancer VL - 100 UR - https://doi.org/10.1038/sj.bjc.6604937 DO - 10.1038/sj.bjc.6604937 ID - Agarwal2009 ER - TY - JOUR AU - Ma, P. C. AU - Jagadeeswaran, R. AU - Jagadeesh, S. AU - Tretiakova, M. S. AU - Nallasura, V. AU - Fox, E. A. AU - Hansen, M. AU - Schaefer, E. AU - Naoki, K. AU - Lader, A. AU - Richards, W. AU - Sugarbaker, D. AU - Husain, A. N. AU - Christensen, J. G. AU - Salgia, R. PY - 2005 DA - 2005// TI - Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer JO - Cancer Res VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-04-2650 DO - 10.1158/0008-5472.CAN-04-2650 ID - Ma2005 ER - TY - JOUR AU - Sattler, M. AU - Salgia, R. PY - 2009 DA - 2009// TI - The MET axis as a therapeutic target JO - Update Cancer Ther VL - 3 UR - https://doi.org/10.1016/j.uct.2009.01.001 DO - 10.1016/j.uct.2009.01.001 ID - Sattler2009 ER - TY - JOUR AU - Sattler, M. AU - Pride, Y. B. AU - Ma, P. AU - Gramlich, J. L. AU - Chu, S. C. AU - Quinnan, L. A. AU - Shirazian, S. AU - Liang, C. AU - Podar, K. AU - Christensen, J. G. AU - Salgia, R. A. PY - 2003 DA - 2003// TI - A novel small molecule Met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase JO - Cancer Res VL - 9 ID - Sattler2003 ER - TY - JOUR AU - Lawrence, R. E. AU - Salgia, R. PY - 2010 DA - 2010// TI - MET molecular mechanisms and therapies in lung cancer JO - Cell Adh Migr VL - 4 UR - https://doi.org/10.4161/cam.4.1.10973 DO - 10.4161/cam.4.1.10973 ID - Lawrence2010 ER - TY - STD TI - Smyth EC, Sclafani E, Cunningham D: Emerging molecular targets in oncology: clinical potential of MET/hepatocyte growth-factor inhibitors. Onco Targets Ther 2014. doi:10.2147/OTT.S44941. Smyth EC, Sclafani E, Cunningham D: Emerging molecular targets in oncology: clinical potential of MET/hepatocyte growth-factor inhibitors.Onco Targets Ther 2014. doi:10.2147/OTT.S44941. ID - ref38 ER - TY - JOUR AU - Tang, Z. AU - Du, R. AU - Jiang, S. AU - Wu, C. AU - Barkauskas, D. S. AU - Richey, J. AU - Molter, J. AU - Lam, M. AU - Flask, C. AU - Gerson, S. AU - Dowlati, A. AU - Liu, L. AU - Lee, Z. AU - Halmos, B. AU - Wang, Y. AU - Dern, J. A. AU - Ma, P. C. PY - 2008 DA - 2008// TI - Dual MET-EGFR combinational inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer JO - Br J Cancer VL - 99 UR - https://doi.org/10.1038/sj.bjc.6604559 DO - 10.1038/sj.bjc.6604559 ID - Tang2008 ER - TY - JOUR AU - Foveau, B. AU - Ancot, F. AU - Leroy, C. AU - Petrelli, A. AU - Reiss, K. AU - Vingtdeux, V. AU - Giordano, S. AU - Fafeur, V. AU - Tulasne, D. PY - 2009 DA - 2009// TI - Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis JO - Mol Biol Cell VL - 20 UR - https://doi.org/10.1091/mbc.E08-09-0969 DO - 10.1091/mbc.E08-09-0969 ID - Foveau2009 ER - TY - JOUR AU - Sierra, J. R. AU - Tsao, M. S. PY - 2011 DA - 2011// TI - c-MET as a potential therapeutic target and biomarker in cancer JO - Ther Adv Med Oncol VL - 3 UR - https://doi.org/10.1177/1758834011422557 DO - 10.1177/1758834011422557 ID - Sierra2011 ER - TY - JOUR AU - Kass, L. AU - Erler, J. T. AU - Dembo, M. AU - Weaver, V. M. PY - 2007 DA - 2007// TI - Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis JO - Int J Biochem Cell Biol VL - 39 UR - https://doi.org/10.1016/j.biocel.2007.06.025 DO - 10.1016/j.biocel.2007.06.025 ID - Kass2007 ER - TY - JOUR AU - Ponzo, M. G. AU - Lesurf, R. AU - Petkiewicz, S. AU - O'Malley, F. P. AU - Pinnaduwage, D. AU - Andrulis, I. L. AU - Bull, S. B. AU - Chughtai, N. AU - Zuo, D. AU - Souleimanova, M. AU - Germain, D. AU - Omeroglu, A. AU - Cardiff, R. D. AU - Hallett, M. AU - Park, M. PY - 2009 DA - 2009// TI - Met induces mammary tumors with diverse histologies and is associated with poor outcome and human breast cancer JO - Proc Natl Acad Sci USA VL - 106 UR - https://doi.org/10.1073/pnas.0810402106 DO - 10.1073/pnas.0810402106 ID - Ponzo2009 ER - TY - JOUR AU - Kim, E. J. AU - Eom, S. J. AU - Hong, J. E. AU - Lee, J. Y. AU - Choi, M. S. AU - Park, J. H. PY - 2012 DA - 2012// TI - Benzyl isothiocyanate inhibits basal and hepatocyte growth factor-stimulated migration of breast cancer cells JO - Mol Cell Biochem VL - 359 UR - https://doi.org/10.1007/s11010-011-1039-3 DO - 10.1007/s11010-011-1039-3 ID - Kim2012 ER - TY - JOUR AU - Berthou, S. AU - Aebersold, D. M. AU - Schmidt, L. S. AU - Stroka, D. AU - Heigl, C. AU - Streit, B. AU - Stalder, D. AU - Gruber, G. AU - Liang, C. AU - Howlett, A. R. AU - Candinas, D. AU - Greiner, R. H. AU - Lipson, K. E. E. AU - Zimmer, Y. PY - 2004 DA - 2004// TI - The Met kinase inhibitor SU11274 exhibits a selective inhibition patter toward different receptor mutated variants JO - Oncogene VL - 23 UR - https://doi.org/10.1038/sj.onc.1207691 DO - 10.1038/sj.onc.1207691 ID - Berthou2004 ER - TY - JOUR AU - Tanizaki, J. AU - Okamoto, I. AU - Sakai, K. AU - Nakagawa, K. PY - 2011 DA - 2011// TI - Differential roles of trans-phosphorylated EGFR, HER2, HER3, and RET as heterodimerisation partners of MET in lung cancer with MET amplification JO - Br J Cancer VL - 105 UR - https://doi.org/10.1038/bjc.2011.322 DO - 10.1038/bjc.2011.322 ID - Tanizaki2011 ER - TY - JOUR AU - Date, K. AU - Matsumoto, K. AU - Kuba, K. AU - Shimura, H. AU - Tanaka, M. AU - Nakamura, T. PY - 1998 DA - 1998// TI - Inhibition of tumor growth and invasion by a four-kringle antagonist (HGF/NK4) for hepatocyte growth factor JO - Oncogene VL - 17 UR - https://doi.org/10.1038/sj.onc.1202231 DO - 10.1038/sj.onc.1202231 ID - Date1998 ER - TY - JOUR AU - Cao, B. AU - Su, Y. AU - Oskarsson, M. AU - Zhao, P. AU - Kort, E. J. AU - Fisher, R. J. AU - Wang, L. M. AU - Vande Woude, G. F. PY - 2001 DA - 2001// TI - Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models JO - Proc Natl Acad Sci USA VL - 98 UR - https://doi.org/10.1073/pnas.131200498 DO - 10.1073/pnas.131200498 ID - Cao2001 ER - TY - JOUR AU - Mazzone, M. AU - Basilico, C. AU - Cavassa, S. AU - Pennacchietti, S. AU - Risio, M. AU - Naldini, L. AU - Comoglio, P. M. AU - Michieli, P. PY - 2004 DA - 2004// TI - An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice JO - J Clin Invest VL - 114 UR - https://doi.org/10.1172/JCI22235 DO - 10.1172/JCI22235 ID - Mazzone2004 ER - TY - JOUR AU - Burgess, T. AU - Coxon, A. AU - Meyer, S. AU - Sun, J. AU - Rex, K. AU - Tsuruda, T. AU - Chen, Q. AU - Ho, S. Y. AU - Li, L. AU - Kaufman, S. AU - McDorman, K. AU - Cattley, R. C. AU - Elliott, G. AU - Zhang, K. AU - Feng, X. AU - Jia, X. C. AU - Green, L. AU - Radinsky, R. AU - Kendall, R. PY - 2006 DA - 2006// TI - Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c- Met-dependent human tumors JO - Cancer Res VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-05-3329 DO - 10.1158/0008-5472.CAN-05-3329 ID - Burgess2006 ER - TY - JOUR AU - Sylvester, P. W. AU - Theriault, A. PY - 2003 DA - 2003// TI - Role of tocotrienols in the prevention of cardiovascular disease and breast cancer JO - Curr Top Nutraceutical Res VL - 1 ID - Sylvester2003 ER - TY - CHAP AU - Sylvester, P. W. ED - Watson, R. R. ED - Preedy, V. R. PY - 2008 DA - 2008// TI - Antiproliferative and apoptotic effects of tocotrienols on normal and neoplastic mammary epithelial cells BT - tocotrienols: vitamin E beyond tocopherols PB - CRC Press CY - Boca Raton UR - https://doi.org/10.1201/9781420080391.ch10 DO - 10.1201/9781420080391.ch10 ID - Sylvester2008 ER - TY - JOUR AU - McIntyre, B. S. AU - Briski, K. P. AU - Tirmenstein, M. AU - Fariss, M. W. AU - Gapor, A. AU - Sylvester, P. W. PY - 2000 DA - 2000// TI - Antiproliferative and apoptotic effects of tocopherols and tocotrienols in normal mouse mammary epithelial cell JO - Lipids VL - 35 UR - https://doi.org/10.1007/BF02664767 DO - 10.1007/BF02664767 ID - McIntyre2000 ER - TY - JOUR AU - McIntyre, B. S. AU - Briski, K. P. AU - Gapor, A. AU - Sylvester, P. W. PY - 2000 DA - 2000// TI - Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells JO - Proc Soc Exp Biol Med VL - 224 UR - https://doi.org/10.1046/j.1525-1373.2000.22434.x DO - 10.1046/j.1525-1373.2000.22434.x ID - McIntyre2000 ER - TY - JOUR AU - Samant, G. V. AU - Sylvester, P. W. PY - 2006 DA - 2006// TI - gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells JO - Cell Prolif VL - 39 UR - https://doi.org/10.1111/j.1365-2184.2006.00412.x DO - 10.1111/j.1365-2184.2006.00412.x ID - Samant2006 ER - TY - JOUR AU - Bachawal, S. V. AU - Wali, V. B. AU - Sylvester, P. W. PY - 2010 DA - 2010// TI - Combined gamma-tocotrienol and erlotinib/gefitinib treatment suppresses Stat and Akt signaling in murine mammary tumor cells JO - Anticancer Res VL - 30 ID - Bachawal2010 ER - TY - JOUR AU - Bachawal, S. V. AU - Wali, V. B. AU - Sylvester, P. W. PY - 2010 DA - 2010// TI - Enhanced antiproliferative and apoptotic response to combined treatment of gamma-tocotrienol with erlotinib or gefitinib in mammary tumor cells JO - BMC Cancer VL - 10 UR - https://doi.org/10.1186/1471-2407-10-84 DO - 10.1186/1471-2407-10-84 ID - Bachawal2010 ER - TY - JOUR AU - Holmgren, L. PY - 1996 DA - 1996// TI - Antiangiogenesis restricted tumor dormancy JO - Cancer Metastasis Rev VL - 15 UR - https://doi.org/10.1007/BF00437478 DO - 10.1007/BF00437478 ID - Holmgren1996 ER - TY - JOUR AU - Semenza, G. L. PY - 1999 DA - 1999// TI - Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1 JO - Annu Rev Cell Dev Biol VL - 15 UR - https://doi.org/10.1146/annurev.cellbio.15.1.551 DO - 10.1146/annurev.cellbio.15.1.551 ID - Semenza1999 ER - TY - JOUR AU - Semenza, G. L. PY - 2000 DA - 2000// TI - HIF-1: using two hands to flip the angiogenic switch JO - Cancer Metastasis Rev VL - 19 UR - https://doi.org/10.1023/A:1026544214667 DO - 10.1023/A:1026544214667 ID - Semenza2000 ER - TY - JOUR AU - Semenza, G. L. PY - 2002 DA - 2002// TI - HIF-1 and tumor progression: pathophysiology and therapeutics JO - Trends Mol Med VL - 8 UR - https://doi.org/10.1016/S1471-4914(02)02317-1 DO - 10.1016/S1471-4914(02)02317-1 ID - Semenza2002 ER - TY - JOUR AU - Josko, J. AU - Gwozdz, B. AU - Jedrzejowska-Szypulka, H. AU - Hendryk, S. PY - 2000 DA - 2000// TI - Vascular endothelial growth factor (VEGF) and its effect on angiogenesis JO - Med Sci Monit VL - 6 ID - Josko2000 ER - TY - STD TI - Ananthula S, Parajuli P, Behery FA, El Sayed KA, Sylvester PW: γ-Tocotrienol oxazine derivative antagonizes mammary tumor cell compensatory responses to CoCl2-induced hypoxia.Biomed Res Int 2014. .[http://dx.doi.org/10.1155/2014/285752]. UR - http://dx.doi.org/10.1155/2014/285752 ID - ref63 ER -