Figure 3
From: Evaluation of lung flute in sputum samples for molecular analysis of lung cancer
Comparison of miRNA biomarkers and sputum cytology for lung cancer diagnosis in 39 patients diagnosed with stage I NSCLC and 42 cancer-free individuals. Analysis of the two miRNAs (miR-31 and miR-210) in sputum produces a higher specificity, a lower specificity compared with sputum cytology. Combined analysis of the miRNAs and cytology presents a higher sensitivity compared with a single approach, maintaining a high specificity at 93.0%. *, statistical significance (P < 0.05).