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Table 1 VOCs of interest

From: Gas signatures from Escherichia coli and Escherichia coli-inoculated human whole blood

Gas

Stat. diff.

Broth

Blood

 

+ E. coli

 

+ E. coli

Category 1: VOCs elevated in E. coli -infected blood

Diemthyl sulfide [pptv]

2,4

970 (310,2310)

16010 (180,29500)

3770 (1250,8820)

95920 (25740,234400)

Carbon disulfide [pptv]

2,3,4

85 (55,470)

295 (80,790)

4390 (2450,10040)

8940 (2620,16550)

Acetaldehyde [ppbv]

 

736 (558,1089)

645 (44,1359)

45 (22,145)

1158 (208,3493)

Ethanol [ppbv]

1,2,3

202 (28,564)

8388 (2037,10867)

218 (5,604)

15486 (7199,40441)

Unk S§

2,3

31 (0,316)

74 (12,267)

675 (0,3311)

15001 (2208,37426)

Methyl Butanoate [pptv]

 

0 (0,25)

0 (0,40)

60 (0,405)

2675 (330,9720)

Category 2: VOCs elevated in naïve E. coli in LB broth

Isoprene [pptv]

1,4

0 (0,50)

1590 (665,2175)

1040 (350,2785)

1200 (455,2050)

Carbonyl sulfide (OCS) [pptv]

1

2240 (1440,4850)

8360 (4360,20180)

3850 (1970,22040)

6540 (3810,30340)

Unk R1§

 

7474 (1568,42622)

116738 (15070,1005677)

3758 (105,20243)

2435 (785,10277)

Category 3: VOCs elevated in naïve E. coli but substantially lower from co-culture of E. coli and whole blood

Dimethyl disulfide [ppbv]

1,3,4

164 (133,185)

354 (182,537)

0.7 (0.3,2)

2 (0.6,4)

Methyl Propanoate [pptv]

 

3300 (2100,4300)

14500 (5660,21000)

400 (0,1400)

600 (0,1100)

Dimethyl trisulfide [pptv]

1,3

2900 (1900,9700)

160400 (22700,253300)

800 (10,6900)

400 (150,5400)

Unk_Q§

 

2052 (0,13997)

57320 (6317,467654)

620 (0,6232)

289 (0,3787)

1-Propanol [pptv]

 

175 (0,90200)

757300 (472900,1920800)

700 (0,93600)

33400 (4100,90200)

Methylcylohexane [pptv]

 

220 (60,990)

1600 (850,3200)

130 (0,1720)

170 (80,980)

Unk R2§

 

416 (0,5269)

15852 (2228,152789)

767 (0,9829)

674 (0,8522)

  1. 1: significantly different between Broth only and Broth + E. coli; 2: significantly different between Blood only and Blood + E. coli; 3: significantly different between Broth + E. coli i and Blood + E. coli; 4: significantly different between Broth only and blood only.
  2. Data were presented with median and range (minimum, maximum).
  3. §unknown peaks were presented as area under the curve.