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Table 1 Proteins observed by mass spectrometry from uninvolved and psoriatic skin of a single patient

From: A pilot study demonstrating a non-invasive method for the measurement of protein turnover in skin disorders: application to psoriasis

Uninvolved skin

# of unique peptides

total peptide count

mol wt (Da)

peptide count/mol wt x 103

Keratin 10

34

91

58827

1.55

Keratin 1

37

95

66039

1.44

Keratin 2

34

66

65433

1.01

Keratin 6A

10

24

60045

0.40

Keratin 77 (Keratin 1B)

16

24

61801

0.39

Keratin 5

11

20

62378

0.32

Keratin 14

5

7

51622

0.14

Glycine-N-acyltransferase isoform b

2

2

18506

0.11

Keratin 6 irs4

3

6

57865

0.10

Glyceraldehyde-3-phosphate dehydrogenase

2

3

36053

0.08

Keratin 9

4

5

62064

0.08

Keratin 5b

3

4

56866

0.07

Transglutaminase 3 precursor

2

2

76731

0.03

Psoriatic skin

# of unique peptides

total peptide count

mol wt (Da)

peptide count/mol wt x 10 3

Keratin 6A

58

191

60045

3.18

Keratin 10

46

147

58827

2.50

Keratin 1

50

128

66039

1.94

Keratin 14

36

92

51622

1.78

Keratin 2

34

81

65433

1.24

Keratin 5

29

58

62378

0.93

Keratin 17

19

44

48106

0.91

Keratin 16

22

46

51268

0.90

Histone cluster 4

4

8

11367

0.70

S100 calcium-binding protein A8

3

7

10834

0.65

Serine (or cysteine) proteinase inhibitor, clade B, member 4

6

14

44854

0.31

Pyruvate kinase, muscle isoform 2

9

18

58062

0.31

Junction plakoglobin

12

22

81745

0.27

  1. Proteins observed by peptide mass spectrometry from uninvolved and psoriatic skin of a single patient. For each protein the number of unique peptides and the total peptide count, which includes multiple observations of the same peptide, are listed. The peptide count has been divided by the molecular weight and proteins are listed in order of the resulting product. All 13 proteins identified from the uninvolved skin of this individual are listed together with the first 13 (of 66 total) proteins seen in psoriatic skin.