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Table 1 Important pathogenic features of nontypeable Haemophilus influenzae

From: Haemophilus influenzae and the lung (Haemophilus and the lung)

Mucociliary interactions Binding to mucus
  Inhibition of ciliary function/death of ciliary cells
Attachment to respiratory mucosa Adhesins
  Hia/Hap proteins
Evasion of mucosal immunity IgA proteases
  Microcolony formation
  Phase variation/antigenic drift
Intracellular survival/invasion of local tissue Survival inside mononuclear phagocytes and epithelial cells
  Extensive invasion of lung parenchyma